Cagrilintide

Chemical & Structural Information

• CAS Number: 1415456-99-3
• Molecular Formula: C194H312N54O59S2
• Molecular Weight: approximately 4,409 g/mol
• Structure: A long-acting, modified amylin analogue with a disulfide bond and a fatty-acid-linked side chain.
• Peptide Length: 38 amino-acid positions in the published sequence.

What It Is

• Cagrilintide is a long-acting research peptide designed to act like amylin, a natural hormone released alongside
insulin after eating.
Research Focus
• Fullness signalling: Amylin-related signalling is involved in telling the brain when enough food has been
eaten.
• Food intake: Clinical research has examined whether cagrilintide can influence appetite and energy intake.
• Body-weight research: Trials have studied cagrilintide alone and together with other metabolic research
compounds, including semaglutide, while measuring changes in body weight.
• Metabolic research: Researchers also monitor glucose-related and other metabolic markers during clinical
studies.

How It Is Studied

• Cagrilintide has progressed into human clinical research. Scientists study its effects on amylin receptors,
appetite signalling, food intake, body weight and metabolic measurements.

Glossary

• Amylin: A natural hormone released with insulin that helps control fullness and digestion.
• Analogue: A molecule designed to behave similarly to a natural substance.
• Receptor: A target on a cell that receives a biological signal.
• Disulfide bond: A strong chemical link that helps hold part of a peptide's shape together.

All Information is Provided for Research Purposes Only