Ipamorelin

Chemical & Structural Information
• Compound type: Synthetic five-amino-acid growth-hormone secretagogue
• CAS Number: 170851-70-4
• Molecular Formula: C38H49N9O5
• Molecular Weight: approximately 711.9 g/mol
• Structure: H-Aib-His-D-2Nal-D-Phe-Lys-NH2

What It Is

Ipamorelin is a synthetic peptide studied for its ability to trigger growth hormone release. It acts on the ghrelin
receptor and has been researched for a more selective hormone profile than some older growth-hormone-releasing
peptides.

Research Focus

• Growth hormone - studied for pulse-like GH release.
• Ghrelin receptor - ipamorelin activates GHSR, a receptor involved in hormone and metabolic signalling.
• Hormone selectivity - preclinical studies compare its effects on GH with hormones such as cortisol and prolactin.
• Endocrine research - scientists use it to study the GH/IGF-1 system.

How It Is Studied

Ipamorelin activates the ghrelin receptor, also called GHSR. This can signal the pituitary gland to release growth
hormone in pulses.

Glossary

• Secretagogue: A substance that causes another substance, such as a hormone, to be released.
• Ghrelin: A natural hormone involved in appetite and GH signalling.
• GHSR: The receptor that responds to ghrelin.
• Pulsatile: Happening in short bursts or pulses.

For Research Purposes Only