KPV

Chemical & Structural Information
• Compound type: Three-amino-acid peptide derived from alpha-MSH
• CAS Number: 67727-97-3
• Molecular Formula: C16H30N4O4
• Molecular Weight: approximately 342.43 g/mol
• Peptide Sequence: KPV | Structural Form: H-Lys-Pro-Val-OH

What It Is

KPV is a very short peptide made from lysine, proline and valine. It comes from the end section of alpha-MSH and is
mainly studied in inflammation, skin and intestinal research.

Research Focus

• Inflammatory signalling - studies look at pathways such as NF-kappaB and inflammatory messenger molecules.
• Gut lining - KPV has been studied in intestinal cells and experimental bowel-inflammation models.
• Immune cells - laboratory work examines how KPV may change immune-cell signalling.
• Skin and barrier research - researchers also study KPV in skin and epithelial tissue models.

How It Is Studied

KPV is only three amino acids long, making it a simple research tool for studying one small active part of alpha-MSH.
Many studies measure its effect on inflammation-related cell signals.

Glossary

• Tripeptide: A peptide made from three amino acids.
• Alpha-MSH: A natural signalling peptide involved in melanocortin biology.
• NF-kappaB: A major cell pathway that controls many inflammation-related genes.
• Epithelial cells: Cells that form surfaces and protective linings.

For Research Purposes Only