Pinealon

Chemical & Structural Information
• CAS Number: 175175-23-2
• Peptide Sequence: Glu-Asp-Arg (EDR)
• Molecular Formula: C15H26N6O8
• Molecular Weight: approximately 418.41 g/mol
• Structure: H-Glu-Asp-Arg-OH
What It Is

• Pinealon is a short three-amino-acid peptide, also known as EDR. It is mainly researched for its possible role in
brain-cell biology, gene activity and protection from cellular stress.

Research Focus

• Brain-cell research: Laboratory and animal studies have examined Pinealon in relation to neuron survival and
normal cell function.
• Oxidative stress: Research has reported effects on reactive oxygen species, which are unstable molecules
that can place stress on cells.
• Neuroplasticity: Studies have explored its effects on dendritic spines, small structures that help nerve cells
communicate.
• Gene regulation: EDR has been investigated for possible effects on genes and proteins linked with antioxidant
defence and neuron activity.

How It Is Studied

• Pinealon research includes cell, animal and limited human studies. Scientists mainly look at memory-related
pathways, neuron structure, oxidative stress and gene expression.

Glossary

• Neuron: A nerve cell that sends information through the brain and nervous system.
• Oxidative stress: Cell stress caused when reactive molecules build up faster than the body can control them.
• Neuroplasticity: The brain's ability to change and form new connections.
• Dendritic spine: A tiny structure on a nerve cell that helps it connect with other nerve cells.

All Information is Provided for Research Purposes Only