Semax

Chemical & Structural Information

• Compound type: Synthetic seven-amino-acid peptide
• CAS Number: 80714-61-0
• Molecular Formula: C37H51N9O10S
• Molecular Weight: approximately 813.9 g/mol
• Peptide Sequence: MEHFPGP | H-Met-Glu-His-Phe-Pro-Gly-Pro-OH

What It Is

Semax is a synthetic peptide based on a small part of ACTH. It is mainly studied in brain and nervous-system
research, especially for gene activity, learning, memory and responses to stress or reduced blood flow.

Research Focus

• Neurotrophic signals - studies measure BDNF, NGF and other proteins linked with nerve-cell growth and function.
• Learning and memory - animal research examines memory and behaviour.
• Brain stress models - Semax has been studied in experimental reduced-blood-flow and injury models.
• Gene activity - researchers have measured changes in genes linked with nervous-system signalling.

How It Is Studied

Semax is studied as a signalling peptide rather than as ACTH itself. Research suggests it can affect pathways linked
with neuroplasticity and growth-factor signalling.

Glossary

• Neurotrophic factor: A protein that supports nerve-cell growth and function.
• BDNF: A brain protein involved in learning and nerve-cell health.
• Neuroplasticity: The brain's ability to change and form new connections.
• Ischaemia: Reduced blood flow to tissue.

For Research Purposes Only